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Quando os oiço... tenho sempre que me recordar que tanto o OFC como o VMPFC não é mesmo a praia deles:
A wealth of animal and human studies suggest that the vmPFC plays a key role in calculating the value of choice outcomes, which guides decision-making in diverse domains (for reviews, see e.g. Bechara & Damasio, 2005; Montague, King-Casas, & Cohen, 2006; Wallis, 2007). Bechara and Damasio (Bechara & Damasio, 2005; Bechara, Damasio, & Damasio, 2000; Damasio, 1994) have argued, in particular, that the vmPFC is a critical neural structure for attaching affective/emotional signals to mental representations of future outcomes. These affective/emotional signals would help individuals to know “what it feels like” to be in a given future situation, thus guiding their decisions in advantageous ways. 2 Patients with damage to the vmPFC indeed seem oblivious to the consequences of their actions, and accordingly present severe impairments of personal and social decision-making in their daily life (e.g., the choices they make often lead to loss of reputation, job, and family), in spite of otherwise largely preserved cognitive abilities (Bechara & Damasio, 2005; Damasio, 1994).
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